Paracetamol orodispersible tablets: a risk for severe poisoning in children?
نویسندگان
چکیده
منابع مشابه
A randomized controlled trial and novel mathematical analysis of the analgesic effect of oxycodone versus paracetamol orodispersible tablets.
BACKGROUND For effective treatment of acute pain, a rapid onset of action is important. Here we quantify the antinociceptive profile of an orodispersible oxycodone tablet (OOT) in a randomized, double-blind, active comparator (paracetamol orodispersible tablet, POT), crossover study design in a population of healthy volunteers. METHODS Twelve female volunteers were randomized to receive 20 mg...
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Introduction: Severe early childhood caries is the presence of smooth-surface caries in children younger than three years of age. This rampant form of dental caries exerts a negative impact on the quality of life of both the child and the family .The purpose of this study was to investigate the risk factors for severe early childhood caries (S-ECC) among 2-3 year-old children in Rasht. Materia...
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A 15 year old girl was admitted 55 hours after taking an unspecified quantity of paracetamol. She was fully conscious and oriented. Her pulse rate was 88 beats/ min regular and blood pressure 110/70 mm Hg. The liver edge was palpable and tender. Plasma paracetamol concentration was 41 mg/I, serum sodium concentration 138 mmol/l, serum potassium concentration 4-2 mmol/l, plasma urea concentratio...
متن کامل[Acute paracetamol poisoning].
Of 41 cases of acute paracetamol poisoning one died of gastrointestinal haemorrhage and acute massive necrosis of the liver, three became jaundiced, and 13 others had biochemical evidence of hepatocellular damage. Liver damage is a toxic effect which is present in most patients who ingest more than 15 g. of paracetamol. One patient with liver damage survived renal failure due to acute tubular n...
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West Midlands Centre for Adverse Drug Reactions, City Hospital, Birmingham, UK School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK National Poisons Information Service, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK University/BHF Centre for Cardiovascular Science, Edinburgh University, Queen’s Medical Research Ins...
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ژورنال
عنوان ژورنال: European Journal of Clinical Pharmacology
سال: 2010
ISSN: 0031-6970,1432-1041
DOI: 10.1007/s00228-010-0943-x